OUR RESEARCH

Funded Research

Aging & Cancer Research Program (2026)

Impact of Aging on the Intestinal Stem Cell Niche and Colorectal Cancer

  • Omer Yilmaz, PhD – Massachusetts Institute of Technology
  • Andrew Chan, MD, MPH – Massachusetts General Hospital

Reducing Aging-Associated Blood Cancers by Understanding How TNFα Signaling Shapes Hematopoietic Stem Cells

  • Jennifer Trowbridge, PhD – The Jackson Laboratory
  • Peter Van Galen, PhD – Brigham and Women’s Hospital

Aging-Associated Inflammation in Lung Cancer Evolution

  • Tuomas Tammela, PhD – Memorial Sloan Kettering Cancer Center
  • Alexander Tsankov, PhD – Icahn School of Medicine at Mount Sinai

Senescence-Associated Metabolism in Age-Related Tumorigenesis

  • Corina Amor, PhD – Cold Spring Harbor Laboratory
  • Joshua Rabinowitz, PhD – Princeton University

Targeting LINE-1 to Prevent Age-Dependent Immune Dysfunction in Cancer

Co-funded with generous support from Cancer Research Institute

  • Miriam Merad, MD, PhD – Icahn School of Medicine at Mount Sinai
  • Nicholas Vabret, PhD – Icahn School of Medicine at Mount Sinai
  • Vera Gorbunova, PhD – University of Rochester

Aging & Cancer Research Program (2024)

Spatiotemporal Profiling of the Aged Microenvironment in Tumor Dormancy and Recurrent Disease

Co-funded with generous support from Melanoma Research Alliance

  • Ashani Weeraratna, PhD – Johns Hopkins University
  • Arjun Raj, PhD – University of Pennsylvania

Mechanisms of Cancer Dormancy Impacted by Clonal Hematopoiesis

  • Julio Aguirre-Ghiso, PhD – Montefiore Einstein Comprehensive Cancer Center
  • Ross Levine, MD – Memorial Sloan Kettering Cancer Center

Improving Breast Cancer Outcomes by Understanding How Immune Age Impacts Tumor Evolution and Response to Therapy

  • Sandra McAllister, PhD – Brigham and Women’s Hospital
  • Kornelia Polyak, MD, PhD – Dana-Farber Cancer Institute
  • Rachel Freedman, MD – Dana-Farber Cancer Institute